published

A mixed integer optimization approach for model selection in screening experiments

After completing the experimental runs of a screening design, the responses under study are analyzed by statistical methods to detect the active effects. To increase the chances of correctly identifying these effects, a good analysis method should …

A nonlinear multidimensional knapsack problem in the optimal design of mixture experiments

Mixture experiments usually involve various constraints on the proportions of the ingredients of the mixture under study. In this paper, inspired by the fact that the available stock of certain ingredients is often limited, we focus on a new type of …

Projections of Definitive Screening Designs by Dropping Columns: Selection and Evaluation

Definitive screening designs permit the study of many quantitative factors in a few runs more than twice the number of factors. In practical applications, researchers often require a design for m quantitative factors, construct a definitive screening …

A simulation-based heuristic that promotes business profit while increasing the perceived quality of service industries

This paper tackles the problem of minimising the direct server costs of complex multiple-server queueing systems while improving the quality perceived by customers. The problem is solved by finding the server roster, defined as the allocation of …

OApackage: A Python package for generation and analysis of orthogonal arrays, optimal designs and conference designs

Construction of Two-Level Nonregular Designs of Strength Three With Large Run Sizes

Two-level orthogonal arrays of strength 3 permit the study of the main effects and the two-factor interactions of the experimental factors. These arrays are classified into regular and nonregular designs. Good regular designs are available in the …

Ruggedness testing of an analytical method for pesticide residues in potato

The best demonstration of the ruggedness of a method is monitoring its performance on an ongoing basis as part of the analytical quality control applied in the laboratory. However, an initial demonstration of the ruggedness is often performed as one …

Constructing Two-Level Designs by Concatenation of Strength-3 Orthogonal Arrays

Two-level orthogonal arrays of N runs, k factors, and a strength of 3 provide suitable fractional factorial designs in situations where many of the main effects are expected to be active, as well as some two-factor interactions. If they consist of …

LADES: A Software for Constructing and Analyzing Longitudinal Designs in Biomedical Research

One of the most important steps in biomedical longitudinal studies is choosing a good experimental design that can provide high accuracy in the analysis of results with a minimum sample size. Several methods for constructing efficient longitudinal …