Subjects with complex and serious diseases, such as malaria and leukemia, can have adverse reactions to the best-known treatments. The personalized medicine approach becomes beneficial because the subjects’ characteristics or covariates are …
Computer experiments can build computationally cheap statistical models to study complex computer models. These experiments are commonly conducted using maximin distance Latin hypercube designs (LHDs), generated using heuristic algorithms or …
Two-level screening designs are widely applied in manufacturing industry to identify influential factors of a system. These designs have each factor at two levels and are traditionally constructed using standard algorithms, which rely on a …
After completing the experimental runs of a screening design, the responses under study are analyzed by statistical methods to detect the active effects. To increase the chances of correctly identifying these effects, a good analysis method should …